A comparative study of odor identification and odor discrimination deficits in Parkinson's disease
Identifieur interne : 002A37 ( Main/Exploration ); précédent : 002A36; suivant : 002A38A comparative study of odor identification and odor discrimination deficits in Parkinson's disease
Auteurs : Sanne Boesveldt [Pays-Bas] ; Dagmar Verbaan [Pays-Bas] ; Dirk L. Knol [Pays-Bas] ; Martine Visser [Pays-Bas] ; Stephanie M. Van Rooden [Pays-Bas] ; Jacobus J. Van Hilten [Pays-Bas] ; Henk W. Berendse [Pays-Bas]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-10-30.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Analysis of Variance, Comparative study, Discrimination, Discrimination (Psychology) (physiology), Female, Humans, Male, Middle Aged, Nervous system diseases, Odor, Odors, Olfaction, Olfaction Disorders (etiology), Olfactory Perception (physiology), Parkinson Disease (complications), Parkinson disease, Parkinson's disease, ROC Curve, ROC curves, Sensory Thresholds, odor discrimination, odor identification, olfaction.
- MESH :
- complications : Parkinson Disease.
- etiology : Olfaction Disorders.
- physiology : Discrimination (Psychology), Olfactory Perception.
- Adult, Aged, Aged, 80 and over, Analysis of Variance, Female, Humans, Male, Middle Aged, Odors, ROC Curve, Sensory Thresholds.
Abstract
The aim of this study was to compare the characteristics of odor discrimination and odor identification deficits in a large population of patients with Parkinson's disease (PD) and to determine which of these olfactory tests best distinguishes between patients with PD and control subjects. Olfactory performance was assessed in 404 patients with PD and 150 controls, using the odor identification and discrimination parts of the Sniffin' Sticks battery. Mean identification and discrimination scores in patients with PD were significantly lower than in controls. Linear regression analysis using a 95% confidence interval revealed that, relative to the performance of controls, 65.0% of patients with PD had an impairment in odor identification, whereas 42.1% of patients were impaired on the odor discrimination task. ROC curves revealed a higher sensitivity and specificity for odor identification than for odor discrimination in separating patients from controls. In patients with PD, odor discrimination performance decreased with increasing disease duration, whereas odor identification was not correlated with disease stage or duration. In PD, odor identification is more frequently impaired than odor discrimination and allows a better discrimination between patients and controls. Although an odor identification deficit is generally believed to be independent of disease progression, the impairment in odor discrimination appears to increase with disease duration. © 2008 Movement Disorder Society
Url:
DOI: 10.1002/mds.22155
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001259
- to stream Istex, to step Curation: 001259
- to stream Istex, to step Checkpoint: 001595
- to stream PubMed, to step Corpus: 002068
- to stream PubMed, to step Curation: 002068
- to stream PubMed, to step Checkpoint: 002471
- to stream Ncbi, to step Merge: 002295
- to stream Ncbi, to step Curation: 002295
- to stream Ncbi, to step Checkpoint: 002295
- to stream Main, to step Merge: 003617
- to stream PascalFrancis, to step Corpus: 001070
- to stream PascalFrancis, to step Curation: 001C49
- to stream PascalFrancis, to step Checkpoint: 001396
- to stream Main, to step Merge: 003A04
- to stream Main, to step Curation: 002A37
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">A comparative study of odor identification and odor discrimination deficits in Parkinson's disease</title>
<author><name sortKey="Boesveldt, Sanne" sort="Boesveldt, Sanne" uniqKey="Boesveldt S" first="Sanne" last="Boesveldt">Sanne Boesveldt</name>
</author>
<author><name sortKey="Verbaan, Dagmar" sort="Verbaan, Dagmar" uniqKey="Verbaan D" first="Dagmar" last="Verbaan">Dagmar Verbaan</name>
</author>
<author><name sortKey="Knol, Dirk L" sort="Knol, Dirk L" uniqKey="Knol D" first="Dirk L." last="Knol">Dirk L. Knol</name>
</author>
<author><name sortKey="Visser, Martine" sort="Visser, Martine" uniqKey="Visser M" first="Martine" last="Visser">Martine Visser</name>
</author>
<author><name sortKey="Van Rooden, Stephanie M" sort="Van Rooden, Stephanie M" uniqKey="Van Rooden S" first="Stephanie M." last="Van Rooden">Stephanie M. Van Rooden</name>
</author>
<author><name sortKey="Van Hilten, Jacobus J" sort="Van Hilten, Jacobus J" uniqKey="Van Hilten J" first="Jacobus J." last="Van Hilten">Jacobus J. Van Hilten</name>
</author>
<author><name sortKey="Berendse, Henk W" sort="Berendse, Henk W" uniqKey="Berendse H" first="Henk W." last="Berendse">Henk W. Berendse</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:C9AAC263D13D2037AEF01678698EFD581F6E196E</idno>
<date when="2008" year="2008">2008</date>
<idno type="doi">10.1002/mds.22155</idno>
<idno type="url">https://api.istex.fr/document/C9AAC263D13D2037AEF01678698EFD581F6E196E/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001259</idno>
<idno type="wicri:Area/Istex/Curation">001259</idno>
<idno type="wicri:Area/Istex/Checkpoint">001595</idno>
<idno type="wicri:doubleKey">0885-3185:2008:Boesveldt S:a:comparative:study</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:18759360</idno>
<idno type="wicri:Area/PubMed/Corpus">002068</idno>
<idno type="wicri:Area/PubMed/Curation">002068</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002471</idno>
<idno type="wicri:Area/Ncbi/Merge">002295</idno>
<idno type="wicri:Area/Ncbi/Curation">002295</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">002295</idno>
<idno type="wicri:Area/Main/Merge">003617</idno>
<idno type="wicri:source">INIST</idno>
<idno type="RBID">Pascal:08-0536665</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">001070</idno>
<idno type="wicri:Area/PascalFrancis/Curation">001C49</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">001396</idno>
<idno type="wicri:doubleKey">0885-3185:2008:Boesveldt S:a:comparative:study</idno>
<idno type="wicri:Area/Main/Merge">003A04</idno>
<idno type="wicri:Area/Main/Curation">002A37</idno>
<idno type="wicri:Area/Main/Exploration">002A37</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">A comparative study of odor identification and odor discrimination deficits in Parkinson's disease</title>
<author><name sortKey="Boesveldt, Sanne" sort="Boesveldt, Sanne" uniqKey="Boesveldt S" first="Sanne" last="Boesveldt">Sanne Boesveldt</name>
<affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, VU University Medical Center, Amsterdam</wicri:regionArea>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Verbaan, Dagmar" sort="Verbaan, Dagmar" uniqKey="Verbaan D" first="Dagmar" last="Verbaan">Dagmar Verbaan</name>
<affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Leiden University Medical Center, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Knol, Dirk L" sort="Knol, Dirk L" uniqKey="Knol D" first="Dirk L." last="Knol">Dirk L. Knol</name>
<affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, VU University Medical Center, Amsterdam</wicri:regionArea>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Visser, Martine" sort="Visser, Martine" uniqKey="Visser M" first="Martine" last="Visser">Martine Visser</name>
<affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Leiden University Medical Center, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Van Rooden, Stephanie M" sort="Van Rooden, Stephanie M" uniqKey="Van Rooden S" first="Stephanie M." last="Van Rooden">Stephanie M. Van Rooden</name>
<affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Leiden University Medical Center, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Van Hilten, Jacobus J" sort="Van Hilten, Jacobus J" uniqKey="Van Hilten J" first="Jacobus J." last="Van Hilten">Jacobus J. Van Hilten</name>
<affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, Leiden University Medical Center, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Berendse, Henk W" sort="Berendse, Henk W" uniqKey="Berendse H" first="Henk W." last="Berendse">Henk W. Berendse</name>
<affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Neurology, VU University Medical Center, Amsterdam</wicri:regionArea>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2008-10-30">2008-10-30</date>
<biblScope unit="vol">23</biblScope>
<biblScope unit="issue">14</biblScope>
<biblScope unit="page" from="1984">1984</biblScope>
<biblScope unit="page" to="1990">1990</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">C9AAC263D13D2037AEF01678698EFD581F6E196E</idno>
<idno type="DOI">10.1002/mds.22155</idno>
<idno type="ArticleID">MDS22155</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Analysis of Variance</term>
<term>Comparative study</term>
<term>Discrimination</term>
<term>Discrimination (Psychology) (physiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Nervous system diseases</term>
<term>Odor</term>
<term>Odors</term>
<term>Olfaction</term>
<term>Olfaction Disorders (etiology)</term>
<term>Olfactory Perception (physiology)</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson disease</term>
<term>Parkinson's disease</term>
<term>ROC Curve</term>
<term>ROC curves</term>
<term>Sensory Thresholds</term>
<term>odor discrimination</term>
<term>odor identification</term>
<term>olfaction</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Olfaction Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Discrimination (Psychology)</term>
<term>Olfactory Perception</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Analysis of Variance</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Odors</term>
<term>ROC Curve</term>
<term>Sensory Thresholds</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Discrimination</term>
<term>Etude comparative</term>
<term>Maladie de Parkinson</term>
<term>Odeur</term>
<term>Olfaction</term>
<term>Pathologie du système nerveux</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The aim of this study was to compare the characteristics of odor discrimination and odor identification deficits in a large population of patients with Parkinson's disease (PD) and to determine which of these olfactory tests best distinguishes between patients with PD and control subjects. Olfactory performance was assessed in 404 patients with PD and 150 controls, using the odor identification and discrimination parts of the Sniffin' Sticks battery. Mean identification and discrimination scores in patients with PD were significantly lower than in controls. Linear regression analysis using a 95% confidence interval revealed that, relative to the performance of controls, 65.0% of patients with PD had an impairment in odor identification, whereas 42.1% of patients were impaired on the odor discrimination task. ROC curves revealed a higher sensitivity and specificity for odor identification than for odor discrimination in separating patients from controls. In patients with PD, odor discrimination performance decreased with increasing disease duration, whereas odor identification was not correlated with disease stage or duration. In PD, odor identification is more frequently impaired than odor discrimination and allows a better discrimination between patients and controls. Although an odor identification deficit is generally believed to be independent of disease progression, the impairment in odor discrimination appears to increase with disease duration. © 2008 Movement Disorder Society</div>
</front>
</TEI>
<affiliations><list><country><li>Pays-Bas</li>
</country>
<region><li>Hollande-Méridionale</li>
<li>Hollande-Septentrionale</li>
</region>
<settlement><li>Amsterdam</li>
<li>Leyde</li>
</settlement>
</list>
<tree><country name="Pays-Bas"><region name="Hollande-Septentrionale"><name sortKey="Boesveldt, Sanne" sort="Boesveldt, Sanne" uniqKey="Boesveldt S" first="Sanne" last="Boesveldt">Sanne Boesveldt</name>
</region>
<name sortKey="Berendse, Henk W" sort="Berendse, Henk W" uniqKey="Berendse H" first="Henk W." last="Berendse">Henk W. Berendse</name>
<name sortKey="Knol, Dirk L" sort="Knol, Dirk L" uniqKey="Knol D" first="Dirk L." last="Knol">Dirk L. Knol</name>
<name sortKey="Van Hilten, Jacobus J" sort="Van Hilten, Jacobus J" uniqKey="Van Hilten J" first="Jacobus J." last="Van Hilten">Jacobus J. Van Hilten</name>
<name sortKey="Van Rooden, Stephanie M" sort="Van Rooden, Stephanie M" uniqKey="Van Rooden S" first="Stephanie M." last="Van Rooden">Stephanie M. Van Rooden</name>
<name sortKey="Verbaan, Dagmar" sort="Verbaan, Dagmar" uniqKey="Verbaan D" first="Dagmar" last="Verbaan">Dagmar Verbaan</name>
<name sortKey="Visser, Martine" sort="Visser, Martine" uniqKey="Visser M" first="Martine" last="Visser">Martine Visser</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002A37 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002A37 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:C9AAC263D13D2037AEF01678698EFD581F6E196E |texte= A comparative study of odor identification and odor discrimination deficits in Parkinson's disease }}
This area was generated with Dilib version V0.6.23. |